Acknowledgements
This work was supported by NANOSAFE (Risk Assessment in Production and Use of Nanoparticles with Development of Preventive Measures and apply Codes) project funded by the eu Community below the "Competitive and property Growth" Programme, Contract G1MA-CT-2002-00020. Full report are often found at http:/ / imperia5.vdi-online.de/ imperia/ md/ content/ tz/ zuknftigetechnologien/ 11.pdf
References
- Feynman R: There's plenty of room at the bottom.
- Ball P: Roll-up for the revolution.
- Salata OV: Application of nanoparticles in biology and medicine.J of Nanobiotechnology 2004, 2:3. BioMed Central Full Text
- Mazzola L: Commercializing nanotechnology.
- Paull R, Wolfe J, Hebert P, Sinkula M: Investing in nanotechnology.Nature Biotechnology 2003, 21:1134-1147. Publisher Full Text
- NanoBusiness Alliance [http://www.nanobusiness.org] webcite2003.
- Luther W, ed: Industrial application of nanomaterials – chances and risks.
- UK Royal Society and Royal Academy of Engineering: Nanoscience and nanotechnologies: opportunities and uncertainties.[http://www.nanotec.org.uk/finalReport.htm] webcite
- Anon: Nanotech is not so scary.
- UK report: More Hits Than Misses on Nanotech[http://www.etcgroup.org/documents/NR_RSfinreport.finaldoc.pdf] webcite
- Nemmar A, Vanbilloen H, Hoylaerts MF, Hoet PH, Verbruggen A, Nemery B: Passage of intratracheally instilled ultrafine particles from the lung into the systemic circulation in hamster.
- Xiang JJ, Tang JQ, Zhu SG, Nie XM, Lu HB, Shen SR, Li XL, Tang K, Zhou M, Li GY: IONP-PLL: a novel non-viral vector for efficient gene delivery.
- Brown DM, Donaldson K, Borm PJ, Schins RP, Dehnhardt M, Gilmour P, Jimenez LA, Stone V: Calcium and ROS-mediated activation of transcription factors and TNF-alpha cytokine gene expression in macrophages exposed to ultrafine particles.
- Zheng M, Jagota A, Strano MS, Santos AP, Barone P, Chou CG, Diner BA, Dresselhaus MS, Mclean RS, Onoa GB, Samsonidze GG, Semke ED, Usrey M, Walls DJ: Structure-based carbon nanotube sorting by sequence-dependent DNA assembly.
- Moolgavkar SH, Brown RC, Turim J: Biopersistence, fiber length, and cancer risk assessment for inhaled fibers.
- Lippmann M: Effects of fiber characteristics on lung deposition, retention, and disease.Environ Health Perspect 1990, 88:311-317. PubMed Abstract
- Moore MA, Brown RC, Pigott G: Material properties of MMVFs and their time-dependent failure in lung environments.
- Oberdorster G: Determinants of the pathogenicity of man-made vitreous fibers (MMVF).
- Oberdorster G: Pulmonary effects of inhaled ultrafine particles.
- Oberdorster G: Toxicokinetics and effects of fibrous and nonfibrous particles.
- Warheit DB, Hart GA, Hesterberg TW, Collins JJ, Dyer WM, Swaen GM, Castranova V, Soiefer AI, Kennedy GL: Potential pulmonary effects of man-made organic fiber (MMOF) dusts.Crit Rev Toxicol 2001, 31:697-736. PubMed Abstract
- Service RF: Nanomaterials show signs of toxicity.
- Warheit DB, Laurence BR, Reed KL, Roach DH, Reynolds GA, Webb TR: Comparative Pulmonary Toxicity Assessment of Single Wall Carbon Nanotubes in Rats.
- Lam CW, James JT, McCluskey R, Hunter RL: Pulmonary Toxicity of Single-Wall Carbon Nanotubes in Mice 7 and 90 Days after Intratracheal Instillation.
- Maynard AD, Baron PA, Foley M, Shvedova AA, Kisin ER, Castranova V: Exposure to Carbon Nanotube Material: Aerosol Release During the Handling of Unrefined Single Walled Carbon Nanotube Material.
- Oberdorster G, Ferin J, Lehnert BE: Correlation between particle size, in vivo particle persistence, and lung injury.Environ Health Perspect 1994, 102:173-179. PubMed Abstract
- Driscoll KE, Deyo LC, Carter JM, Howard BW, Hassenbein DG, Bertram TA: Effects of particle exposure and particle-elicited inflammatory cells on mutation in rat alveolar epithelial cells.
- Oberdorster G, Yu CP: Lung dosimetry – considerations for noninhalation studies.
- Heinrich U, Muhle H, Hoymann HG, Mermelstein R: Pulmonary function changes in rats after chronic and subchronic inhalation exposure to various particulate matter.Exp Pathol 1989, 37:248-252. PubMed Abstract
- Lee KP, Kelly DP, Schneider PW, Trochimowicz HJ: Inhalation toxicity study on rats exposed to titanium tetrachloride atmospheric hydrolysis products for two years.
- Lee KP, Kelly DP, Schneider PW, Trochimowicz HJ: Inhalation toxicity study on rats exposed to titanium tetrachloride atmospheric hydrolysis products for two years.
- Hoet PH, Gilissen L, Nemery B: Polyanions protect against the in vitro pulmonary toxicity of polycationic paint components associated with the Ardystil syndrome.
- Hoet PH, Gilissen LP, Leyva M, Nemery B: In vitro cytotoxicity of textile paint components linked to the "Ardystil syndrome".
- Fischer D, Li Y, Ahlemeyer B, Krieglstein J, Kissel T: In vitro cytotoxicity testing of polycations: influence of polymer structure on cell viability and hemolysis.
- Morgan DM, Clover J, Pearson JD: Effects of synthetic polycations on leucine incorporation, lactate dehydrogenase release, and morphology of human umbilical vein endothelial cells.J Cell Sci 1988, 91:231-238. PubMed Abstract
- Morgan DM, Larvin VL, Pearson JD: Biochemical characterisation of polycation-induced cytotoxicity to human vascular endothelial cells.J Cell Sci 1989, 94:553-559. PubMed Abstract
- Haensler J, Szoka FC: Polyamidoamine cascade polymers mediate efficient transfection of cells in culture.Bioconjug Chem 1993, 4:372-379. PubMed Abstract
- Fischer D, Bieber T, Li Y, Elsasser HP, Kissel T: A novel non-viral vector for DNA delivery based on low molecular weight, branched polyethylenimine: effect of molecular weight on transfection efficiency and cytotoxicity.
- Dekie L, Toncheva V, Dubruel P, Schacht EH, Barrett L, Seymour LW: Poly-L-glutamic acid derivatives as vectors for gene therapy.
- Ryser HJ: A membrane effect of basic polymers dependent on molecular size.Nature 1967, 215:934-936. PubMed Abstract
- Singh AK, Kasinath BS, Lewis EJ: Interaction of polycations with cell surface negative charges of epithelial cells.Biochim Biophys Acta 1992, 1120:337-342. PubMed Abstract
- Geiser M, Schurch S, Gehr P: Influence of surface chemistry and topography of particles on their immersion into the lung's surface-lining layer.
- Gehr P, Geiser M, Hof VI, Schurch S: Surfactant ultrafine particle interactions: what we can learn from PM10 studies.
- Schins RP, Duffin R, Hohr D, Knaapen AM, Shi T, Weishaupt C, Stone V, Donaldson K, Borm PJ: Surface modification of quartz inhibits toxicity, particle uptake, and oxidative DNA damage in human lung epithelial cells.
- Fubini B: Surface Reactivity in the Pathogenic Response to Particulates.Environ Health Perspect 1997, 105:1013-1020. PubMed Abstract
- Yeates DB, Mauderly JL: Inhaled environmental/occupational irritants and allergens: mechanisms of cardiovascular and systemic responses: Introduction.
- Gold DR, Litonjua A, Schwartz J, Lovett E, Larson A, Nearing B, Allen G, Verrier M, Cherry R, Verrier R: Ambient pollution and heart rate variability.
- Liao D, Creason J, Shy C, Williams R, Watts R, Zweidinger R: Daily variation of particulate air pollution and poor cardiac autonomic control in the elderly.
- Conhaim RL, Eaton A, Staub NC, Heath TD: Equivalent pore estimate for the alveolar-airway barrier in isolated dog lung.
- Hermans C, Knoops B, Wiedig M, Arsalane K, Toubeau G, Falmagne P, Bernard A: Clara cell protein as a marker of Clara cell damage and bronchoalveolar blood barrier permeability.
- Florence AT, Hussain N: Transcytosis of nanoparticle and dendrimer delivery systems: evolving vistas.
- Brown JS, Zeman KL, Bennett WD: Ultrafine particle deposition and clearance in the healthy and obstructed lung.
- Kawakami K, Iwamura A, Goto E, Mori Y, Abe T, Hirasaw Y, Ishida H, Shimada T, Tominaga G: Kinetics and clinical application of 99mTc-technegas.Kaku Igaku 1990, 27:725-733. PubMed Abstract
- Steiner S, Pfutzner A, Wilson BR, Harzer O, Heinemann L, Rave K: Technosphere/Insulin – proof of concept study with a new insulin formulation for pulmonary delivery.
- Kreyling W, Semmler M, Erbe F, Mayer P, Schulz H, Oberdorster G, Ziesenis A:Translocation of ultrafine insoluble iridium particles from lung epithelium to extrapulmonary organs is size dependent but very low.
- Oberdorster G, Sharp Z, Atudorei V, Elder A, Gelein R, Lunts A, Kreyling W, Cox C:Extrapulmonary translocation of ultrafine carbon particle following whole-body inhalation exposure of rats.
- Takenaka S, Karg E, Roth C, Schulz H, Ziesenis A, Heinzmann U, Schramel P, Heyder J:Pulmonary and systemic distribution of inhaled ultrafine silver particles in rats.
- Eyles JE, Bramwell VW, Williamsson ED, Alpar HO: Microsphere translocation and immunopotentiation in systemic tissues following intranasal administration.
- Kato T, Yashiro T, Murata Y, Herbert DC, Oshikawa K, Bando M, Ohno S, Sugiyama Y:Evidence that exogenous substances can be phagocytized by alveolar epithelial cells and transported into blood capillaries.
- International Labour Organisation: Safety in the use of mineral and synthetic fibres; working document and report of the meeting of experts on safety in the use of mineral and synthetic fibres, Geneva, 17–25 April 1989.
- Searl A: A review of the durability of inhaled fibers and options for the design of safer fibers.
- Stanton MF, Laynard M, Tegeris A, Miller E, May M, Kent E: Carcinogenicity of fibrous glass: pleural response in the rat in relation to fiber dimension.J Natl Cancer Inst 1977, 58:587-603. PubMed Abstract
- Stanton MF, Wrench C: Mechanisms of mesothelioma induction with asbestos and fibrous glass.J Natl Cancer Inst 1972, 48:797-821. PubMed Abstract
- Berman DW, Crump KS, Chatfield EJ, Davis JM, Jones AD: The sizes, shapes, and mineralogy of asbestos structures that induce lung tumors or mesothelioma in AF/HAN rats following inhalation.Risk Anal 1995, 15:181-195. PubMed Abstract
- Schins RP: Mechanisms of genotoxicity of particles and fibers.
- Hussain N, Jaitley V, Florence AT: Recent advances in the understanding of uptake of microparticulates across the gastrointestinal lymphatics.
- Aprahamian M, Michel C, Humbert W, Devissaguet JP, Damge C: Transmucosal passage of polyalkylcyanoacrylate nanocapsules as a new drug carrier in the small intestine.Biol Cell 1987, 61:69-76. PubMed Abstract
- Hillyer JF, Albrecht RM: Gastrointestinal persorption and tissue distribution of differently sized colloidal gold nanoparticles.
- Jani P, Halbert GW, Langridge J, Florence AT: The uptake and translocation of latex nanospheres and microspheres after oral administration to rats.J Pharm Pharmacol 1989, 41:809-812. PubMed Abstract
- Hussain N, Florence AT: Utilizing bacterial mechanisms of epithelial cell entry: invasin-induced oral uptake of latex nanoparticles.
- Hussain N, Jani PU, Florence AT: Enhanced oral uptake of tomato lectin conjugated nanoparticles in the rat.
- Hillery AM, Jani PU, Florence AT: Comparative, quantitative study of lymphoid and non-lymphoid uptake of 60 nm polystyrene particles.J Drug Target 1994, 2:151-156. PubMed Abstract
- Woodley JF: Lectins for gastrointestinal targeting – 15 years on.J Drug Target 2000, 7:325-333. PubMed Abstract
- Szentkuti L: Light microscopical observations on luminally administered dyes, dextrans, nanospheres and microspheres in the pre-epithelial mucus gel layer of the rat distal colon.J Control Release 1997, 46:233-242. Publisher Full Text
- Jani P, Halbert GW, Langridge J, Florence AT: Nanoparticle uptake by the rat gastrointestinal mucosa: quantitation and particle size dependency.J Pharm Pharmacol 1990, 42:821-826. PubMed Abstract
- Lomer MC, Thompson RP, Powell JJ: Fine and ultrafine particles of the diet: influence on the mucosal immune response and association with Crohn's disease.
- Kucharzik T, Lugering A, Lugering N, Rautenberg K, Linnepe M, Cichon C, Reichelt R, Stoll R, Schmidt MA, Domschke W: Characterization of M cell development during indomethacin-induced ileitis in rats.
- Powell JJ, Harvey RS, Ashwood P, Wolstencroft R, Gershwin ME, Thompson RP: Immune potentiation of ultrafine dietary particles in normal subjects and patients with inflammatory bowel disease.
- Hopwood D, Spiers EM, Ross PE, Anderson JT, McCullough JB, Murray FE: Endocytosis of fluorescent microspheres by human oesophageal epithelial cells: comparison between normal and inflamed tissue.Gut 1995, 37:598-602. PubMed Abstract
- McMinn LH, Hodges GM, Carr KE: Gastrointestinal uptake and translocation of microparticles in the streptozotocin-diabetic rat.J Anat 1996, 189:553-559. PubMed Abstract
- Limpanussorn J, Simon L, Dayan AD: Intestinal uptake of particulate material by dexamethasone-treated rats: use of a novel technique to avoid intestinal mucosal contamination.J Pharm Pharmacol 1998, 50:745-751. PubMed Abstract
- Lademann J, Weigmann H, Rickmeyer C, Barthelmes H, Schaefer H, Mueller G, Sterry W:Penetration of titanium dioxide microparticles in a sunscreen formulation into the horny layer and the follicular orifice.
- Kreilgaard M: Influence of microemulsions on cutaneous drug delivery.
- Tinkle SS, Antonini JM, Rich BA, Roberts JR, Salmen R, DePree K, Adkins EJ: Skin as a route of exposure and sensitization in chronic beryllium disease.
- Menon GK, Elias PM: Morphologic basis for a pore-pathway in mammalian stratum corneum.Skin Pharmacol 1997, 10:235-246. PubMed Abstract
- Andersson KG, Fogh CL, Byrne MA, Roed J, Goddard AJ, Hotchkiss SA: Radiation dose implications of airborne contaminant deposition to humans.
- Lademann J, Otberg N, Richter H, Weigmann HJ, Lindemann U, Schaefer H, Sterry W:Investigation of follicular penetration of topically applied substances.
- de Jalon EG, Blanco-Prieto MJ, Ygartua P, Santoyo S: PLGA microparticles: possible vehicles for topical drug delivery.
- Blundell G, Henderson WJ, Price EW: Soil particles in the tissues of the foot in endemic elephantiasis of the lower legs.Ann Trop Med Parasitol 1989, 83:381-385. PubMed Abstract
- Corachan M: Endemic Non-Filarial Elephantiasis of Lower-Limbs – Podoconiosis.Medicina Clinica 1988, 91:97-100. PubMed Abstract
- Verma DD, Verma S, Blume G, Fahr A: Particle size of liposomes influences dermal delivery of substances into skin.
- Saunders J, Davis H, Coetzee L, Botha S, Kruger A, Grobler A: A novel skin penetration enhancer: evaluation by membrane diffusion and confocal microscopy.
- Hostynek JJ: Factors determining percutaneous metal absorption.
- Labhasetwar V, Song C, Humphrey W, Shebuski R, Levy RJ: Arterial uptake of biodegradable nanoparticles: effect of surface modifications.
- Peters A, Dockery DW, Muller JE, Mittleman MA: Increased particulate air pollution and the triggering of myocardial infarction.
- Nemmar A, Hoylaerts MF, Hoet PH, Dinsdale D, Smith T, Xu H, Vermylen J, Nemery B:Ultrafine particles affect experimental thrombosis in an in vivo hamster model.
- Nemmar A, Hoylaerts MF, Hoet PH, Vermylen J, Nemery B: Size effect of intratracheally instilled particles on pulmonary inflammation and vascular thrombosis.
- Peters A, Doring A, Wichmann HE, Koenig W: Increased plasma viscosity during an air pollution episode: a link to mortality?
- Peters A, Liu E, Verrier RL, Schwartz J, Gold DR, Mittleman M, Baliff J, Oh JA, Allen G, Monahan K, Dockery DW: Air pollution and incidence of cardiac arrhythmia.
- Akerman ME, Chan WC, Laakkonen P, Bhatia SN, Ruoslahti E: Nanocrystal targeting in vivo.Proc Natl Acad Sci US A 2002, 99:12617-12621. Publisher Full Text
- Davda J, Labhasetwar V: Characterization of nanoparticle uptake by endothelial cells.
- Boland S, Baeza-Squiban A, Fournier T, Houcine O, Gendron MC, Chevrier M, Jouvenot G, Coste A, Aubier M, Marano F: Diesel exhaust particles are taken up by human airway epithelial cells in vitro and alter cytokine production.
- Juvin P, Fournier T, Boland S, Soler P, Marano F, Desmonts JM, Aubier M: Diesel particles are taken up by alveolar type II tumor cells and alter cytokines secretion.Arch Environ Health 2002, 57:53-60. PubMed Abstract
- Hoet PH, Nemery B: Stimulation of phagocytosis by ultrafine particles.
- Lundborg M, Johard U, Lastbom L, Gerde P, Camner P: Human alveolar macrophage phagocytic function is impaired by aggregates of ultrafine carbon particles.
- Mossman BT, Sesko AM: In vitro assays to predict the pathogenicity of mineral fibers.
- Oberdorster G: Lung particle overload: implications for occupational exposures to particles.
- Fernandez-Urrusuno R, Fattal E, Feger J, Couvreur P, Therond P: Evaluation of hepatic antioxidant systems after intravenous administration of polymeric nanoparticles.
- Powell JJ, Ainley CC, Harvey RS, Mason IM, Kendall MD, Sankey EA, Dhillon AP, Thompson RP: Characterisation of inorganic microparticles in pigment cells of human gut associated lymphoid tissue.Gut 1996, 38:390-395. PubMed Abstract
- Oberdorster G, Sharp Z, Atudorei V, Elder A, Gelein R, Lunts A, Kreyling W, Cox C:Extrapulmonary translocation of ultrafine carbon particles following whole-body inhalation exposure of rats.
- Pratten MK, Lloyd JB: Uptake of microparticles by rat visceral yolk sac.Placenta 1997, 18:547-552. PubMed Abstract
- Alyaudtin RN, Reichel A, Lobenberg R, Ramge P, Kreuter J, Begley DJ: Interaction of poly(butylcyanoacrylate) nanoparticles with the blood-brain barrier in vivo and in vitro.J Drug Target 2001, 9:209-221. PubMed Abstract
- Pulfer SK, Ciccotto SL, Gallo JM: Distribution of small magnetic particles in brain tumor-bearing rats.
- Schroeder U, Sommerfeld P, Ulrich S, Sabel BA: Nanoparticle technology for delivery of drugs across the blood-brain barrier.
- Kreuter J: Nanoparticulate systems for brain delivery of drugs.
- Araujo L, Lobenberg R, Kreuter J: Influence of the surfactant concentration on the body distribution of nanoparticles.J Drug Target 1999, 6:373-385. PubMed Abstract
- known and unknown health risks - Nanoparticles (1. Introduction & 2. General background)
- known and unknown health risks - Nanoparticles (3. Lung & 2. 4. Intestinal tract)
- known and unknown health risks - Nanoparticles (5. Skin & 6. Body distribution and systemic effects of particulates)
- known and unknown health risks - Nanoparticles (7. Differences in conditions between the lung and intestinal tract & 8. Conclusions)
- known and unknown health risks - Nanoparticles (Acknowledgements - References)
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