Thursday, November 8, 2012

known and unknown health risks - Nanoparticles (Acknowledgements - References)


This work was supported by NANOSAFE (Risk Assessment in Production and Use of Nanoparticles with Development of Preventive Measures and apply Codes) project funded by the eu Community below the "Competitive and property Growth" Programme, Contract G1MA-CT-2002-00020. Full report are often found at http:/ / imperia/ md/ content/ tz/ zuknftigetechnologien/ 11.pdf


  1. Feynman R: There's plenty of room at the bottom.
    Science 1991, 254:1300-1301. OpenURL
  2. Ball P: Roll-up for the revolution.
    Nature 2001, 414:142-144. PubMed Abstract | Publisher Full Text OpenURL
  3. Salata OV: Application of nanoparticles in biology and medicine.
    J of Nanobiotechnology 2004, 2:3. BioMed Central Full Text OpenURL
  4. Mazzola L: Commercializing nanotechnology.
    Nature Biotechnology 2003, 21:1137-1143. PubMed Abstract | Publisher Full Text OpenURL
  5. Paull R, Wolfe J, Hebert P, Sinkula M: Investing in nanotechnology.
    Nature Biotechnology 2003, 21:1134-1147. Publisher Full Text OpenURL
  6. NanoBusiness Alliance [http://www.nanobusiness.orgwebcite
  7. Luther W, ed: Industrial application of nanomaterials – chances and risks.
    Future Technologies 2004, 54:1-112. OpenURL
  8. UK Royal Society and Royal Academy of Engineering: Nanoscience and nanotechnologies: opportunities and uncertainties.[
    Final Report 2004. OpenURL
  9. Anon: Nanotech is not so scary.
    Nature 2003, 421:299. OpenURL
  10. UK report: More Hits Than Misses on Nanotech[
    Action Group on Erosion, Technology and Concentration (ETC) 2004. OpenURL
  11. Nemmar A, Vanbilloen H, Hoylaerts MF, Hoet PH, Verbruggen A, Nemery B: Passage of intratracheally instilled ultrafine particles from the lung into the systemic circulation in hamster.
    Am J Respir Crit Care Med 2001, 164:1665-1668. PubMed Abstract | Publisher Full Text OpenURL
  12. Xiang JJ, Tang JQ, Zhu SG, Nie XM, Lu HB, Shen SR, Li XL, Tang K, Zhou M, Li GY: IONP-PLL: a novel non-viral vector for efficient gene delivery.
    J Gene Med 2003, 5:803-817. PubMed Abstract | Publisher Full Text OpenURL
  13. Brown DM, Donaldson K, Borm PJ, Schins RP, Dehnhardt M, Gilmour P, Jimenez LA, Stone V: Calcium and ROS-mediated activation of transcription factors and TNF-alpha cytokine gene expression in macrophages exposed to ultrafine particles.
    Am J Physiol Lung Cell Mol Physiol 2004, 286:L344-353. PubMed Abstract |Publisher Full Text OpenURL
  14. Zheng M, Jagota A, Strano MS, Santos AP, Barone P, Chou CG, Diner BA, Dresselhaus MS, Mclean RS, Onoa GB, Samsonidze GG, Semke ED, Usrey M, Walls DJ: Structure-based carbon nanotube sorting by sequence-dependent DNA assembly.
    Science 2003, 302:1543-1548. PubMed Abstract | Publisher Full Text OpenURL
  15. Moolgavkar SH, Brown RC, Turim J: Biopersistence, fiber length, and cancer risk assessment for inhaled fibers.
    Inhal Toxicol 2001, 13:755-772. PubMed Abstract | Publisher Full Text OpenURL
  16. Lippmann M: Effects of fiber characteristics on lung deposition, retention, and disease.
    Environ Health Perspect 1990, 88:311-317. PubMed Abstract OpenURL
  17. Moore MA, Brown RC, Pigott G: Material properties of MMVFs and their time-dependent failure in lung environments.
    Inhal Toxicol 2001, 13:1117-1149. PubMed Abstract | Publisher Full Text OpenURL
  18. Oberdorster G: Determinants of the pathogenicity of man-made vitreous fibers (MMVF).
    Int Arch Occup Environ Health 2000, 73:S60-S68. PubMed Abstract | Publisher Full Text OpenURL
  19. Oberdorster G: Pulmonary effects of inhaled ultrafine particles.
    Int Arch Occup Environ Health 2001, 74:1-8. PubMed Abstract | Publisher Full Text OpenURL
  20. Oberdorster G: Toxicokinetics and effects of fibrous and nonfibrous particles.
    Inhal Toxicol 2002, 14:29-56. PubMed Abstract | Publisher Full Text OpenURL
  21. Warheit DB, Hart GA, Hesterberg TW, Collins JJ, Dyer WM, Swaen GM, Castranova V, Soiefer AI, Kennedy GL: Potential pulmonary effects of man-made organic fiber (MMOF) dusts.
    Crit Rev Toxicol 2001, 31:697-736. PubMed Abstract OpenURL
  22. Service RF: Nanomaterials show signs of toxicity.
    Science 2003, 300:243. PubMed Abstract | Publisher Full Text OpenURL
  23. Warheit DB, Laurence BR, Reed KL, Roach DH, Reynolds GA, Webb TR: Comparative Pulmonary Toxicity Assessment of Single Wall Carbon Nanotubes in Rats.
    Toxicol Sci 2003, 77:117-125. PubMed Abstract | Publisher Full Text OpenURL
  24. Lam CW, James JT, McCluskey R, Hunter RL: Pulmonary Toxicity of Single-Wall Carbon Nanotubes in Mice 7 and 90 Days after Intratracheal Instillation.
    Toxicol Sci 2003, 77:126-134. PubMed Abstract | Publisher Full Text OpenURL
  25. Maynard AD, Baron PA, Foley M, Shvedova AA, Kisin ER, Castranova V: Exposure to Carbon Nanotube Material: Aerosol Release During the Handling of Unrefined Single Walled Carbon Nanotube Material.
    J Toxicol Environ Health 2004, 67:87-107. OpenURL
  26. Oberdorster G, Ferin J, Lehnert BE: Correlation between particle size, in vivo particle persistence, and lung injury.
    Environ Health Perspect 1994, 102:173-179. PubMed Abstract OpenURL
  27. Driscoll KE, Deyo LC, Carter JM, Howard BW, Hassenbein DG, Bertram TA: Effects of particle exposure and particle-elicited inflammatory cells on mutation in rat alveolar epithelial cells.
    Carcinogenesis 1997, 18:423-430. PubMed Abstract | Publisher Full Text OpenURL
  28. Oberdorster G, Yu CP: Lung dosimetry – considerations for noninhalation studies.
    Exp Lung Res 1999, 25:1-6. PubMed Abstract | Publisher Full Text OpenURL
  29. Heinrich U, Muhle H, Hoymann HG, Mermelstein R: Pulmonary function changes in rats after chronic and subchronic inhalation exposure to various particulate matter.
    Exp Pathol 1989, 37:248-252. PubMed Abstract OpenURL
  30. Lee KP, Kelly DP, Schneider PW, Trochimowicz HJ: Inhalation toxicity study on rats exposed to titanium tetrachloride atmospheric hydrolysis products for two years.
    Toxicol Appl Pharmacol 1986, 83:30-45. PubMed Abstract | Publisher Full Text OpenURL
  31. Lee KP, Kelly DP, Schneider PW, Trochimowicz HJ: Inhalation toxicity study on rats exposed to titanium tetrachloride atmospheric hydrolysis products for two years.
    Toxicol Appl Pharmacol 1986, 83:30-45. PubMed Abstract | Publisher Full Text OpenURL
  32. Hoet PH, Gilissen L, Nemery B: Polyanions protect against the in vitro pulmonary toxicity of polycationic paint components associated with the Ardystil syndrome.
    Toxicol Appl Pharmacol 2001, 175:184-190. PubMed Abstract | Publisher Full Text OpenURL
  33. Hoet PH, Gilissen LP, Leyva M, Nemery B: In vitro cytotoxicity of textile paint components linked to the "Ardystil syndrome".
    Toxicol Sci 1999, 52:209-216. PubMed Abstract | Publisher Full Text OpenURL
  34. Fischer D, Li Y, Ahlemeyer B, Krieglstein J, Kissel T: In vitro cytotoxicity testing of polycations: influence of polymer structure on cell viability and hemolysis.
    Biomaterials 2003, 24:1121-1131. PubMed Abstract | Publisher Full Text OpenURL
  35. Morgan DM, Clover J, Pearson JD: Effects of synthetic polycations on leucine incorporation, lactate dehydrogenase release, and morphology of human umbilical vein endothelial cells.
    J Cell Sci 1988, 91:231-238. PubMed Abstract OpenURL
  36. Morgan DM, Larvin VL, Pearson JD: Biochemical characterisation of polycation-induced cytotoxicity to human vascular endothelial cells.
    J Cell Sci 1989, 94:553-559. PubMed Abstract OpenURL
  37. Haensler J, Szoka FC: Polyamidoamine cascade polymers mediate efficient transfection of cells in culture.
    Bioconjug Chem 1993, 4:372-379. PubMed Abstract OpenURL
  38. Fischer D, Bieber T, Li Y, Elsasser HP, Kissel T: A novel non-viral vector for DNA delivery based on low molecular weight, branched polyethylenimine: effect of molecular weight on transfection efficiency and cytotoxicity.
    Pharm Res 1999, 16:1273-1279. PubMed Abstract | Publisher Full Text OpenURL
  39. Dekie L, Toncheva V, Dubruel P, Schacht EH, Barrett L, Seymour LW: Poly-L-glutamic acid derivatives as vectors for gene therapy.
    J Control Release 2000, 65:187-202. PubMed Abstract | Publisher Full Text OpenURL
  40. Ryser HJ: A membrane effect of basic polymers dependent on molecular size.
    Nature 1967, 215:934-936. PubMed Abstract OpenURL
  41. Singh AK, Kasinath BS, Lewis EJ: Interaction of polycations with cell surface negative charges of epithelial cells.
    Biochim Biophys Acta 1992, 1120:337-342. PubMed Abstract OpenURL
  42. Geiser M, Schurch S, Gehr P: Influence of surface chemistry and topography of particles on their immersion into the lung's surface-lining layer.
    J Appl Physiol 2003, 94:1793-1801. PubMed Abstract | Publisher Full Text OpenURL
  43. Gehr P, Geiser M, Hof VI, Schurch S: Surfactant ultrafine particle interactions: what we can learn from PM10 studies.
    Phil Trans R Soc Lond A 2000, 358:2707-2718. OpenURL
  44. Schins RP, Duffin R, Hohr D, Knaapen AM, Shi T, Weishaupt C, Stone V, Donaldson K, Borm PJ: Surface modification of quartz inhibits toxicity, particle uptake, and oxidative DNA damage in human lung epithelial cells.
    Chem Res Toxicol 2002, 15:1166-1173. PubMed Abstract | Publisher Full Text OpenURL
  45. Fubini B: Surface Reactivity in the Pathogenic Response to Particulates.
    Environ Health Perspect 1997, 105:1013-1020. PubMed Abstract OpenURL
  46. Yeates DB, Mauderly JL: Inhaled environmental/occupational irritants and allergens: mechanisms of cardiovascular and systemic responses: Introduction.
    Environ Health Perspect 2001, 109:479-481. PubMed Abstract | Publisher Full Text OpenURL
  47. Gold DR, Litonjua A, Schwartz J, Lovett E, Larson A, Nearing B, Allen G, Verrier M, Cherry R, Verrier R: Ambient pollution and heart rate variability.
    Circulation 2000, 101:1267-1273. PubMed Abstract | Publisher Full Text OpenURL
  48. Liao D, Creason J, Shy C, Williams R, Watts R, Zweidinger R: Daily variation of particulate air pollution and poor cardiac autonomic control in the elderly.
    Environ Health Perspect 1999, 107:521-525. PubMed Abstract | Publisher Full Text OpenURL
  49. Conhaim RL, Eaton A, Staub NC, Heath TD: Equivalent pore estimate for the alveolar-airway barrier in isolated dog lung.
    J Appl Physiol 1988, 64:1134-1142. PubMed Abstract | Publisher Full Text OpenURL
  50. Hermans C, Knoops B, Wiedig M, Arsalane K, Toubeau G, Falmagne P, Bernard A: Clara cell protein as a marker of Clara cell damage and bronchoalveolar blood barrier permeability.
    Eur Respir J 1999, 13:1014-1021. PubMed Abstract | Publisher Full Text OpenURL
  51. Florence AT, Hussain N: Transcytosis of nanoparticle and dendrimer delivery systems: evolving vistas.
    Adv Drug Deliv Rev 2001, 50:S69-S89. PubMed Abstract | Publisher Full Text OpenURL
  52. Brown JS, Zeman KL, Bennett WD: Ultrafine particle deposition and clearance in the healthy and obstructed lung.
    Am J Respir Crit Care Med 2002, 166:1240-1247. PubMed Abstract | Publisher Full Text OpenURL
  53. Kawakami K, Iwamura A, Goto E, Mori Y, Abe T, Hirasaw Y, Ishida H, Shimada T, Tominaga G: Kinetics and clinical application of 99mTc-technegas.
    Kaku Igaku 1990, 27:725-733. PubMed Abstract OpenURL
  54. Steiner S, Pfutzner A, Wilson BR, Harzer O, Heinemann L, Rave K: Technosphere/Insulin – proof of concept study with a new insulin formulation for pulmonary delivery.
    Exp Clin Endocrinol Diabetes 2002, 110:17-21. PubMed Abstract | Publisher Full Text OpenURL
  55. Kreyling W, Semmler M, Erbe F, Mayer P, Schulz H, Oberdorster G, Ziesenis A:Translocation of ultrafine insoluble iridium particles from lung epithelium to extrapulmonary organs is size dependent but very low.
    J Toxicol Environ Health A 2002, 65:1513-1530. PubMed Abstract | Publisher Full Text OpenURL
  56. Oberdorster G, Sharp Z, Atudorei V, Elder A, Gelein R, Lunts A, Kreyling W, Cox C:Extrapulmonary translocation of ultrafine carbon particle following whole-body inhalation exposure of rats.
    J Toxicol Environ Health A 2002, 65:1531-1543. PubMed Abstract | Publisher Full Text OpenURL
  57. Takenaka S, Karg E, Roth C, Schulz H, Ziesenis A, Heinzmann U, Schramel P, Heyder J:Pulmonary and systemic distribution of inhaled ultrafine silver particles in rats.
    Environ Health Perspect 2001, 109:547-551. PubMed Abstract | Publisher Full Text OpenURL
  58. Eyles JE, Bramwell VW, Williamsson ED, Alpar HO: Microsphere translocation and immunopotentiation in systemic tissues following intranasal administration.
    Vaccine 2001, 19:4732-4742. PubMed Abstract | Publisher Full Text OpenURL
  59. Kato T, Yashiro T, Murata Y, Herbert DC, Oshikawa K, Bando M, Ohno S, Sugiyama Y:Evidence that exogenous substances can be phagocytized by alveolar epithelial cells and transported into blood capillaries.
    Cell Tissue Res 2003, 311:47-51. PubMed Abstract | Publisher Full Text OpenURL
  60. International Labour Organisation: Safety in the use of mineral and synthetic fibres; working document and report of the meeting of experts on safety in the use of mineral and synthetic fibres, Geneva, 17–25 April 1989.
    Occupational Safety and Health Series 1990, 64:1-94. OpenURL
  61. Searl A: A review of the durability of inhaled fibers and options for the design of safer fibers.
    Annals of Occupational Hygiene 1994, 38:839-855. OpenURL
  62. Stanton MF, Laynard M, Tegeris A, Miller E, May M, Kent E: Carcinogenicity of fibrous glass: pleural response in the rat in relation to fiber dimension.
    J Natl Cancer Inst 1977, 58:587-603. PubMed Abstract OpenURL
  63. Stanton MF, Wrench C: Mechanisms of mesothelioma induction with asbestos and fibrous glass.
    J Natl Cancer Inst 1972, 48:797-821. PubMed Abstract OpenURL
  64. Berman DW, Crump KS, Chatfield EJ, Davis JM, Jones AD: The sizes, shapes, and mineralogy of asbestos structures that induce lung tumors or mesothelioma in AF/HAN rats following inhalation.
    Risk Anal 1995, 15:181-195. PubMed Abstract OpenURL
  65. Schins RP: Mechanisms of genotoxicity of particles and fibers.
    Inhal Toxicol 2002, 14:57-78. PubMed Abstract | Publisher Full Text OpenURL
  66. Hussain N, Jaitley V, Florence AT: Recent advances in the understanding of uptake of microparticulates across the gastrointestinal lymphatics.
    Adv Drug Deliv Rev 2001, 50:107-142. PubMed Abstract | Publisher Full Text OpenURL
  67. Aprahamian M, Michel C, Humbert W, Devissaguet JP, Damge C: Transmucosal passage of polyalkylcyanoacrylate nanocapsules as a new drug carrier in the small intestine.
    Biol Cell 1987, 61:69-76. PubMed Abstract OpenURL
  68. Hillyer JF, Albrecht RM: Gastrointestinal persorption and tissue distribution of differently sized colloidal gold nanoparticles.
    J Pharm Sci 2001, 90:1927-1936. PubMed Abstract | Publisher Full Text OpenURL
  69. Jani P, Halbert GW, Langridge J, Florence AT: The uptake and translocation of latex nanospheres and microspheres after oral administration to rats.
    J Pharm Pharmacol 1989, 41:809-812. PubMed Abstract OpenURL
  70. Hussain N, Florence AT: Utilizing bacterial mechanisms of epithelial cell entry: invasin-induced oral uptake of latex nanoparticles.
    Pharm Res 1998, 15:153-156. PubMed Abstract | Publisher Full Text OpenURL
  71. Hussain N, Jani PU, Florence AT: Enhanced oral uptake of tomato lectin conjugated nanoparticles in the rat.
    Pharm Res 1997, 14:613-618. PubMed Abstract | Publisher Full Text OpenURL
  72. Hillery AM, Jani PU, Florence AT: Comparative, quantitative study of lymphoid and non-lymphoid uptake of 60 nm polystyrene particles.
    J Drug Target 1994, 2:151-156. PubMed Abstract OpenURL
  73. Woodley JF: Lectins for gastrointestinal targeting – 15 years on.
    J Drug Target 2000, 7:325-333. PubMed Abstract OpenURL
  74. Szentkuti L: Light microscopical observations on luminally administered dyes, dextrans, nanospheres and microspheres in the pre-epithelial mucus gel layer of the rat distal colon.
    J Control Release 1997, 46:233-242. Publisher Full Text OpenURL
  75. Jani P, Halbert GW, Langridge J, Florence AT: Nanoparticle uptake by the rat gastrointestinal mucosa: quantitation and particle size dependency.
    J Pharm Pharmacol 1990, 42:821-826. PubMed Abstract OpenURL
  76. Lomer MC, Thompson RP, Powell JJ: Fine and ultrafine particles of the diet: influence on the mucosal immune response and association with Crohn's disease.
    Proc Nutr Soc 2002, 61:123-130. PubMed Abstract | Publisher Full Text OpenURL
  77. Kucharzik T, Lugering A, Lugering N, Rautenberg K, Linnepe M, Cichon C, Reichelt R, Stoll R, Schmidt MA, Domschke W: Characterization of M cell development during indomethacin-induced ileitis in rats.
    Aliment Pharmacol Ther 2000, 14:247-256. PubMed Abstract | Publisher Full Text OpenURL
  78. Powell JJ, Harvey RS, Ashwood P, Wolstencroft R, Gershwin ME, Thompson RP: Immune potentiation of ultrafine dietary particles in normal subjects and patients with inflammatory bowel disease.
    J Autoimmun 2000, 14:99-105. PubMed Abstract | Publisher Full Text OpenURL
  79. Hopwood D, Spiers EM, Ross PE, Anderson JT, McCullough JB, Murray FE: Endocytosis of fluorescent microspheres by human oesophageal epithelial cells: comparison between normal and inflamed tissue.
    Gut 1995, 37:598-602. PubMed Abstract OpenURL
  80. McMinn LH, Hodges GM, Carr KE: Gastrointestinal uptake and translocation of microparticles in the streptozotocin-diabetic rat.
    J Anat 1996, 189:553-559. PubMed Abstract OpenURL
  81. Limpanussorn J, Simon L, Dayan AD: Intestinal uptake of particulate material by dexamethasone-treated rats: use of a novel technique to avoid intestinal mucosal contamination.
    J Pharm Pharmacol 1998, 50:745-751. PubMed Abstract OpenURL
  82. Lademann J, Weigmann H, Rickmeyer C, Barthelmes H, Schaefer H, Mueller G, Sterry W:Penetration of titanium dioxide microparticles in a sunscreen formulation into the horny layer and the follicular orifice.
    Skin Pharmacol Appl Skin Physiol 1999, 12:247-256. PubMed Abstract | Publisher Full Text OpenURL
  83. Kreilgaard M: Influence of microemulsions on cutaneous drug delivery.
    Adv Drug Deliv Rev 2002, 54:S77-S98. PubMed Abstract | Publisher Full Text OpenURL
  84. Tinkle SS, Antonini JM, Rich BA, Roberts JR, Salmen R, DePree K, Adkins EJ: Skin as a route of exposure and sensitization in chronic beryllium disease.
    Environ Health Perspect 2003, 111:1202-1208. PubMed Abstract | Publisher Full Text OpenURL
  85. Menon GK, Elias PM: Morphologic basis for a pore-pathway in mammalian stratum corneum.
    Skin Pharmacol 1997, 10:235-246. PubMed Abstract OpenURL
  86. Andersson KG, Fogh CL, Byrne MA, Roed J, Goddard AJ, Hotchkiss SA: Radiation dose implications of airborne contaminant deposition to humans.
    Health Phys 2002, 82:226-232. PubMed Abstract | Publisher Full Text OpenURL
  87. Lademann J, Otberg N, Richter H, Weigmann HJ, Lindemann U, Schaefer H, Sterry W:Investigation of follicular penetration of topically applied substances.
    Skin Pharmacol Appl Skin Physiol 2001, 14:17-22. PubMed Abstract | Publisher Full Text OpenURL
  88. de Jalon EG, Blanco-Prieto MJ, Ygartua P, Santoyo S: PLGA microparticles: possible vehicles for topical drug delivery.
    Int J Pharm 2001, 226:181-184. PubMed Abstract | Publisher Full Text OpenURL
  89. Blundell G, Henderson WJ, Price EW: Soil particles in the tissues of the foot in endemic elephantiasis of the lower legs.
    Ann Trop Med Parasitol 1989, 83:381-385. PubMed Abstract OpenURL
  90. Corachan M: Endemic Non-Filarial Elephantiasis of Lower-Limbs – Podoconiosis.
    Medicina Clinica 1988, 91:97-100. PubMed Abstract OpenURL
  91. Verma DD, Verma S, Blume G, Fahr A: Particle size of liposomes influences dermal delivery of substances into skin.
    Int J Pharm 2003, 258:141-151. PubMed Abstract | Publisher Full Text OpenURL
  92. Saunders J, Davis H, Coetzee L, Botha S, Kruger A, Grobler A: A novel skin penetration enhancer: evaluation by membrane diffusion and confocal microscopy.
    J Pharm Pharm Sci 1999, 2:99-107. PubMed Abstract | Publisher Full Text OpenURL
  93. Hostynek JJ: Factors determining percutaneous metal absorption.
    Food Chem Toxicol 2003, 41:327-345. PubMed Abstract | Publisher Full Text OpenURL
  94. Labhasetwar V, Song C, Humphrey W, Shebuski R, Levy RJ: Arterial uptake of biodegradable nanoparticles: effect of surface modifications.
    J Pharm Sci 1998, 87:1229-1234. PubMed Abstract | Publisher Full Text OpenURL
  95. Peters A, Dockery DW, Muller JE, Mittleman MA: Increased particulate air pollution and the triggering of myocardial infarction.
    Circulation 2001, 103:2810-2815. PubMed Abstract | Publisher Full Text OpenURL
  96. Nemmar A, Hoylaerts MF, Hoet PH, Dinsdale D, Smith T, Xu H, Vermylen J, Nemery B:Ultrafine particles affect experimental thrombosis in an in vivo hamster model.
    Am J Respir Crit Care Med 2002, 166:998-1004. PubMed Abstract | Publisher Full Text OpenURL
  97. Nemmar A, Hoylaerts MF, Hoet PH, Vermylen J, Nemery B: Size effect of intratracheally instilled particles on pulmonary inflammation and vascular thrombosis.
    Toxicol Appl Pharmacol 2003, 186:38-45. PubMed Abstract | Publisher Full Text OpenURL
  98. Peters A, Doring A, Wichmann HE, Koenig W: Increased plasma viscosity during an air pollution episode: a link to mortality?
    Lancet 1997, 349:1582-1587. PubMed Abstract | Publisher Full Text OpenURL
  99. Peters A, Liu E, Verrier RL, Schwartz J, Gold DR, Mittleman M, Baliff J, Oh JA, Allen G, Monahan K, Dockery DW: Air pollution and incidence of cardiac arrhythmia.
    Epidemiology 2000, 11:11-17. PubMed Abstract | Publisher Full Text OpenURL
  100. Akerman ME, Chan WC, Laakkonen P, Bhatia SN, Ruoslahti E: Nanocrystal targeting in vivo.
    Proc Natl Acad Sci US A 2002, 99:12617-12621. Publisher Full Text OpenURL
  101. Davda J, Labhasetwar V: Characterization of nanoparticle uptake by endothelial cells.
    Int J Pharm 2002, 233:51-59. PubMed Abstract | Publisher Full Text OpenURL
  102. Boland S, Baeza-Squiban A, Fournier T, Houcine O, Gendron MC, Chevrier M, Jouvenot G, Coste A, Aubier M, Marano F: Diesel exhaust particles are taken up by human airway epithelial cells in vitro and alter cytokine production.
    Am J Physiol 1999, 276:L604-L613. PubMed Abstract | Publisher Full Text OpenURL
  103. Juvin P, Fournier T, Boland S, Soler P, Marano F, Desmonts JM, Aubier M: Diesel particles are taken up by alveolar type II tumor cells and alter cytokines secretion.
    Arch Environ Health 2002, 57:53-60. PubMed Abstract OpenURL
  104. Hoet PH, Nemery B: Stimulation of phagocytosis by ultrafine particles.
    Toxicol Appl Pharmacol 2001, 176:203. PubMed Abstract | Publisher Full Text OpenURL
  105. Lundborg M, Johard U, Lastbom L, Gerde P, Camner P: Human alveolar macrophage phagocytic function is impaired by aggregates of ultrafine carbon particles.
    Environ Res 2001, 86:244-253. PubMed Abstract | Publisher Full Text OpenURL
  106. Mossman BT, Sesko AM: In vitro assays to predict the pathogenicity of mineral fibers.
    Toxicology 1990, 60:53-61. PubMed Abstract | Publisher Full Text OpenURL
  107. Oberdorster G: Lung particle overload: implications for occupational exposures to particles.
    Regul Toxicol Pharmacol 1995, 21:123-135. PubMed Abstract | Publisher Full Text OpenURL
  108. Fernandez-Urrusuno R, Fattal E, Feger J, Couvreur P, Therond P: Evaluation of hepatic antioxidant systems after intravenous administration of polymeric nanoparticles.
    Biomaterials 1997, 18:511-517. PubMed Abstract | Publisher Full Text OpenURL
  109. Powell JJ, Ainley CC, Harvey RS, Mason IM, Kendall MD, Sankey EA, Dhillon AP, Thompson RP: Characterisation of inorganic microparticles in pigment cells of human gut associated lymphoid tissue.
    Gut 1996, 38:390-395. PubMed Abstract OpenURL
  110. Oberdorster G, Sharp Z, Atudorei V, Elder A, Gelein R, Lunts A, Kreyling W, Cox C:Extrapulmonary translocation of ultrafine carbon particles following whole-body inhalation exposure of rats.
    J Toxicol Environ Health A 2002, 65:1531-1543. PubMed Abstract | Publisher Full Text OpenURL
  111. Pratten MK, Lloyd JB: Uptake of microparticles by rat visceral yolk sac.
    Placenta 1997, 18:547-552. PubMed Abstract OpenURL
  112. Alyaudtin RN, Reichel A, Lobenberg R, Ramge P, Kreuter J, Begley DJ: Interaction of poly(butylcyanoacrylate) nanoparticles with the blood-brain barrier in vivo and in vitro.
    J Drug Target 2001, 9:209-221. PubMed Abstract OpenURL
  113. Pulfer SK, Ciccotto SL, Gallo JM: Distribution of small magnetic particles in brain tumor-bearing rats.
    J Neurooncol 1999, 41:99-105. PubMed Abstract | Publisher Full Text OpenURL
  114. Schroeder U, Sommerfeld P, Ulrich S, Sabel BA: Nanoparticle technology for delivery of drugs across the blood-brain barrier.
    J Pharm Sci 1998, 87:1305-1307. PubMed Abstract | Publisher Full Text OpenURL
  115. Kreuter J: Nanoparticulate systems for brain delivery of drugs.
    Adv Drug Deliv Rev 2001, 47:65-81. PubMed Abstract | Publisher Full Text OpenURL
  116. Araujo L, Lobenberg R, Kreuter J: Influence of the surfactant concentration on the body distribution of nanoparticles.
    J Drug Target 1999, 6:373-385. PubMed Abstract OpenURL

  1. known and unknown health risks - Nanoparticles (1. Introduction & 2. General background)
  2. known and unknown health risks - Nanoparticles (3. Lung & 2. 4. Intestinal tract)
  3. known and unknown health risks - Nanoparticles (5. Skin & 6. Body distribution and systemic effects of particulates)
  4. known and unknown health risks - Nanoparticles (7. Differences in conditions between the lung and intestinal tract & 8. Conclusions)
  5. known and unknown health risks - Nanoparticles (Acknowledgements - References)

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